Lupin (up 0.27 per cent) and Alkem Laboratories (up 0.22 per cent) were among the top gainers.
Aurobindo Pharma (down 1.03 per cent), Divis Laboratories (down 0.82 per cent), Dr Reddys Laboratories (down 0.66 per cent), Biocon (down 0.58 per cent) and Cadila Healthcare (down 0.5 per cent) were the top losers on the index.
The Nifty Pharma index was down 0.41 per cent at 14271.5 at the time of writing this report.
Benchmark NSE Nifty50 index was down 79.95 points at 17289.3, while the BSE Sensex was down 207.8 points at 58097.27.
Among the 50 stocks in the Nifty index, 14 were trading in the green, while 35 were in the red.
Shares of Vodafone Idea, YES Bank, Trident Ltd, NALCO and SAIL were among the most traded shares on the NSE.
Shares of ABM International L, Rex Pipes and Cables Industries Ltd., DU Digital Technologies Ltd., Apcotex Ind and SterlingWilson Solar hit their fresh 52-week highs in today’s trade, while Nandani Creation, Jiya Eco Products Lt, Varroc Engg. and Suvidhaa Infoserve Ltd. hit fresh 52-week lows in trade.